Tube-in-Tube Flow Reactors Webinar from the BIOOX EU-FP7 Project

BIOOX
Funded by the EU as part of the Seventh Framework Programme, the project BIOOX“Developing a validated platform for the application of oxygen dependent enzymes in synthesis and transformation of alcohols” was completed at teh end of September 2017.

Now available via the project website is a second webinar on Tube-in-Tube flow reactors for the rapid kinetic characterisation of enzymes.

Developing a Strategy for Industrial Biotechnology and Bioenergy in the UK

In March 2017 RSM was commissioned by a consortium of four BBSRC NIBB, acting on behalf of the members of all 13 networks, to produce a report on the UK’s industrial biotechnology landscape. The report is available in full here and summary here.

The report was launched on the 31st October at an invited event held in Sheffield and attended by almost 90 delegates drawn from academia, industry, and other key stakeholders. We will be working in the coming months to engage further with those people and other stakeholders who weren’t able to attend the launch in order to develop and implement an action plan that delivers the recommendations of the report. If you would like to comment or contribute to those efforts, then please contact the NIBB Network Managers.

IBCarb & BIOCATNET: Bioactive Polysaccharides, 12th-13th September 2017

Tuesday 12th September, 12 noon – Wednesday 13th September 2017, 1.30pm, Clare College, Cambridge, UK

BIOCATNET IBCarb Joint LogoDue to advances in the tools available to study carbohydrates, polysaccharides have been found to participate in many biological processes which has led to a growing area of research in the use of these “bioactive” polysaccharides. In addition, there is growing interest in the use of carbohydrates, as sustainable alternatives to fossil fuels, and their sustainable advanced manufacture via biotechnology and synthetic biology approaches.

BIOCATNET & IBioIC: Biohalogenation meeting, June 13th 2017

This meeting will review the current status of microbial halogenation and aims to stimulate discussion towards new technologies and potential applications in this area.

Selective halogenation is widely used for tuning the properties of high value bio-actives, particularly in the pharmaceuticals and agrochemicals sectors. In that context halogenation is achieved entirely by chemical methods, and such processes present environmental challenges. For these reasons biocatalytic methods for halogenation, although rare, are attractive.

Speakers:

Rebecca Goss (University of St Andrews)
Deng Hai (University of Aberdeen)
Jason Micklefield (University of Manchester)
Cormac Murphy (University College Dublin)
David O’Hagan (University of St Andrews)

The Chemistry and Biology of Natural Products Symposium XI, 29th-30th June 2017

On the 29th-30th June, the University of Warwick will host the eleventh annual meeting exploring the chemistry and biology of natural products covering subjects from synthetic chemistry to microbial genetics.

This two-day symposium is aimed at postgraduate students, PDRAs and young academics but is also open to any academic/industrialist working in any areas of natural product chemistry and biology.

CBMNET AND BIOCATNET: IMPORT AND EXPORT OF SMALL MOLECULES FOR BIOCATALYSIS

12th-13th September 2017, Waldorf Astoria, The Caledonian, Princes Street, Edinburgh EH1 2AB

Biochemists and microbiologists have long seen whole-cell biocatalysis as an area with great promise for chemical synthesis, for instance to address co-factor recycling or to enable construction of non-natural biosynthetic cascades, however significant challenges occur when substrate and product cannot be easily imported and exported from the cell. This event brings together academic scientists with diverse interests in the import and export of small molecules, alongside industrial scientists who are interested in improving the robustness of whole-cell biocatalysts.

BIOCATNET 4th Call for Proof-of-Concept Proposals

Status: OPEN
Application deadline: 18th April 2017, 5pm

Summary

The 4th Call for BIOCATNET Proof-of-Concept funding, which will fund projects with a total combined value of £250,000, supporting projects in the Network subthemes of Biocatalyst Discovery, Development, and Scale Up.

This Call was developed during the Industrial Biotechnology in the Development of Advanced Materials Workshop held 16th-17th January 2017 at The Principal Manchester, Oxford Road, Manchester, Manchester.

Members who are interesting in applying for funding are strongly encouraged to engage with industrial members to ensure that their proposal demonstrates the widest possible potential impact and industrial relevance. Funding will be available to BIOCATNET members to support short-term Proof-of-Concept projects, preferably within the range of 1-6 months duration. Proposals for long projects must be of the highest possible impact, and will therefore require exceptional justification.

Proof-of-concept projects are designed to stimulate collaborations between BIOCATNET members leading to further applications for funding. The awards will support short-term, precompetitive research projects and scoping exercises in order to de-risk future research and development projects, thereby increasing chances of success and opportunities for uptake of biocatalysis in industry. Awards will support high quality integrated research and development projects that bring together key academic and business components of the UK Industrial Biotechnology and Bioenergy community.

More information on BIOCATNET Proof-of-Concept funding, including guidance on the scope of projects, can be found on the POC Funding page, here. See Proof-of-Concept Project Guidelines for further details. See the Application Form.

All applicants must be members of BIOCATNET – JOIN HERE

UPDATED: Industrial Biotechnology in the Development of Advanced Materials

BIOCATNET - LoginWorkshop to be held 16th-17th January 2017 at The Principal Manchester (formerly, Palace Hotel), Oxford Road, Manchester

Registration: CLOSED

Advanced materials outperform conventional materials and have either superior mechanical, physical, chemical, biological, etc. properties, or have lower environmental impact in use or manufacture, compared with traditional materials. Advanced materials have been acknowledged as key enablers to economic and societal development, and are one of the UK Government’s “Eight Great Technologies” and are vital to address global grand challenges in health, low carbon transport and sustainable energy production.

Innovation in materials involves multi-disciplinary science, has cross-cutting impacts on other technology areas (e.g., nanotechnology, photonics), and enables novel advanced manufacturing techniques. Industrial biotechnology (IB) plays a key role in the development and manufacture of entire classes of material by use of enzymes and biotransformations that access novel chemistries, allow tailorable selectivities and use more benign reaction conditions. IB has revolutionised our ability to synthesise molecules of choice, and has made huge strides into industrial catalysis, pharmaceutical manufacture and biofuel production.

This workshop looks at how enzyme-based IB can improve materials’ manufacture, by improving process sustainability or by enhancing product functionality. The products may be produced or modified by enzymatic routes, or may include the enzymes as a main functional element of the end product.

The workshop aims to match IB solutions to the challenges presented by industrially focussed researchers.

PhD opportunity: Engineering spatial segregation within bacterial hosts for bio-therapeutic protein production

Dr Steffi Frank, a new lecturer in the Department of Biochemical Engineering at UCL has PhD opportunity on micro compartments for protein folding and production.

More information can be found on PRiSM and on FindaPhD:
https://www.prism.ucl.ac.uk/#!/?project=209
https://www.findaphd.com/search/ProjectDetails.aspx?PJID=80249&LID=981

The overall aim of this project is to develop an alternative method to traditional disulphide bond formation approaches (folding in the eukaryotic endoplasmic reticulum and in the periplasm of prokaryotes) by engineering compartmentalisation within the bacterial cytoplasm of bacteria such as E. coli which will allow for an environment that promotes correct protein folding and disulphide bond formation of recombinant proteins.