ABCA4 Rabbit Polyclonal Antibody

Description: A sandwich quantitative ELISA assay kit for detection of Human ATP Binding Cassette Transporter A4 (ABCA4) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human ATP Binding Cassette Transporter A4 (ABCA4) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A polyclonal antibody against ABCA4. Recognizes ABCA4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

Description: A polyclonal antibody against ABCA4. Recognizes ABCA4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

Description: Mouse monoclonal ABCA4 antibody

Description: A polyclonal antibody raised in Goat that recognizes and binds to Human ABCA4 (C-Term). This antibody is tested and proven to work in the following applications:

Description: Antibody raised against ABCA4

Description: Antibody raised against ABCA4

Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Description: Unconjugated Rabbit polyclonal to ABCA4

Description: ABCA4 Peptide

Description: ABCA4 Peptide

Description: Mouse polyclonal to ABCA4

Description: A polyclonal antibody raised in Goat that recognizes and binds to Human ABCA4 (aa1336-49) (internal region). This antibody is tested and proven to work in the following applications:

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4)

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter A4 (ABCA4). This antibody is labeled with PE.

Description: Description of target: In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.128 ng/mL

Description: Description of target: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, and the gene product mediates transport of an essental molecule, all-trans-retinal aldehyde (atRAL), across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 38pg/mL

Description: Description of target: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein was the first of the ABC transporters to be observed in photoreceptors and may play a role in the photoresponse. Mutations in the human gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and macular degeneration age-related 2.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078ng/mL

Description: A Monoclonal antibody against Human ABCA4 (Rim Protein). The antibodies are raised in Mouse and are from clone 3F4. This antibody is applicable in IHC