Brain Targeted Gold Liposomes Improve RNAi Delivery for Glioblastoma.
Glioblastoma (GBM) is the most typical and deadly of the central nervous system (CNS) malignancies. The initiation, development, and infiltration skill of GBMs are attributed partially to the dysregulation of microRNAs (miRNAs). Thus, focusing on dysregulated miRNAs with RNA oligonucleotides (RNAinterference, RNAi) has been proposed for GBM remedy. Despite promising leads to the laboratory, RNA oligonucleotides have...