Malaria management applications implementing Long-Lasting Insecticidal Nets (LLINs) are inspired to conduct subject monitoring of nets’ survival, cloth integrity and insecticidal bio-efficacy. The reference technique for testing the insecticide exercise of LLINs wants 100 two-to-five-day-old feminine mosquitoes per web, which is extremely resource-intensive.
We geared toward figuring out another protocol, utilizing fewer mosquitos, whereas guaranteeing a precision in the primary indicator of ±5 share factors (pp). We in contrast totally different laboratory strategies towards the likelihood of the LLIN to fail the check as decided by a hierarchical Bayesian mannequin. When utilizing 50 mosquitoes per LLIN and contemplating mortality solely as an alternative of mortality or knock-down as validity standards, the common error within the measure of the proportion of nets thought-about as legitimate was 0.40 pp.
The 95% confidence interval of this worth by no means exceed 5 pp when the quantity of LLIN examined was ≥40. This technique barely outperforms the present suggestions. As a conclusion, testing the bio-efficacy of LLINs with half as many mosquitoes offers a sound analysis of the proportion of legitimate LLINs. This strategy might enhance entomology labs’ testing capability and reduce prices, with no influence within the resolution course of for public well being functions.
Softness Induced Enhancement in Net Throughput of Non-Linear Bio-Fluids in Nanofluidic Channel below EDL Phenomenon.
In this text, we describe the electro-hydrodynamics of non-Newtonian fluid in slender fluidic channel with solvent permeable and ion-penetrable polyelectrolyte layer (PEL) grafted on channel floor with an interplay of non-overlapping electrical double layer (EDL) phenomenon. In this evaluation, we combine power-law mannequin within the momentum equation for describing the non-Newtonian rheology.
The complicated interaction between the non-Newtonian rheology and interfacial electrochemistry in presence of PEL on the partitions results in non-intuitive variations within the underlying stream dynamics within the channels. As such, we convey out the variations in stream dynamics and their implications on the web throughput within the channel in phrases of totally different parameters like power-law index (n), drag parameter (α), PEL thickness (d) and Debye size ratio (κ/κ PEL ) are mentioned.
We present, on this evaluation, a relative enhancement within the web throughput by a comfortable nanofluidic channel for each the shear-thinning and shear-thickening fluids, attributed to the stronger electrical physique forces stemming from ionic interactions between polyelectrolyte layer and electrolyte layer. Also, we illustrate that increased obvious viscosity inherent with the category of shear-thickening fluid weakens the softness induced enhancement within the volumetric stream charge for the shear-thickening fluids, for the reason that viscous drag provided to the f low f ield turns into increased for the transport of shear-thickening fluid.
Bio-efficacy of LifeNet, a deltamethrin included long-lasting insecticidal web, as assessed in experimental huts towards Anopheles fluviatilis, a serious malaria vector in east-central India.
LifeNet, a deltamethrin included long-lasting insecticidal (polypropylene) web (LLIN), was certified by the World Health Organization Pesticide Evaluation Scheme (WHOPES) for Phase-II trial in India. The function of this trial was to evaluate the bio-efficacy of unwashed and 20 and 30 occasions washed LifeNet compared to the nets conventionally handled with deltamethrin towards the pure inhabitants of Anopheles fluviatilis, a serious malaria vector, in phrases of deterring hut entry, inhibiting blood feeding, inducing exophily and inflicting mortality.
The trial was carried out in six experimental huts constructed at Kandhaguda village in Malkangiri district, Odisha State. The efficacy of unwashed and washed (20 or 30 occasions) LifeNet was in contrast with untreated polypropylene and conventionally handled (with deltamethrin) polyester web washed to only earlier than exhaustion or washed 20 occasions.
The research confirmed a major discount of entry (remedy: 1.61-4.78; management: 7.61 per hut) and a rise in exit (50.7-64.4% and 39.1%) of An. fluviatilis within the handled arms in comparison with the management arm (untreated web) (P < 0.05). Blood feeding charges diminished in handled arms (20.7-68.0%) in comparison with the management (80.3%) (P < 0.05).
Total mortality was considerably increased in LifeNet arms (73.8-98.3%) than the management (2.2%) (P < 0.05). After 30 washes, the lively ingredient (AI) retention in LifeNet was 62%. Performance of the three LifeNet arms towards the vulnerable inhabitants of An. fluviatilis met the WHO efficacy standards of Phase II analysis for LLINs.
WHO cone bio-assays of classical and new-generation long-lasting insecticidal nets name for modern pesticides focusing on the knock-down resistance mechanism in Benin.
To enhance the effectiveness of insecticide-treated nets (ITN) in areas of excessive resistance, new long-lasting insecticidal nets (LLINs) referred to as new-generation nets have been developed. These nets are handled with the piperonyl butoxide (PBO) synergist which inhibit the motion of detoxing enzymes.
 hsa-miR-580 Primers |
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| MPH01878 | ABM | 150 ul / 10 uM | EUR 121 |
 Antibody) PTPN11 (Ab-580) Antibody |
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| CSB-PA961746- | Cusabio | EUR 335 | |
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Description: A polyclonal antibody against PTPN11 (Ab-580). Recognizes PTPN11 (Ab-580) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 |
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PTPN11 (Ab-580) Antibody |
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| CSB-PA961746-100ul | Cusabio | 100ul | EUR 316 |
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Description: A polyclonal antibody against PTPN11 (Ab-580). Recognizes PTPN11 (Ab-580) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 |
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 MemBriteâ„¢ Fix 568/580 |
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| 30095 | Biotium | 1KIT | EUR 644 |
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Description: Minimum order quantity: 1 unit of 1KIT |
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 Safflower yellow |
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| HY-N0938 | MedChemExpress | 50mg | EUR 133 |
 Antibody) Phospho-PYK2 (Tyr579/580) Antibody |
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| AF7383 | Affbiotech | 200ul | EUR 376 |
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Description: Phospho-PYK2 (Tyr579/580) Antibody detects endogenous levels of PYK2 only when phosphorylated at Tyr579/580. |
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) anti-SHP-2 (Ab-580) |
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| LF-PA20454 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to SHP-2 |
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 hsa-miR-580 miRNA Inhibitor |
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| MIH03164 | ABM | 2 x 5.0 nmol | EUR 176 |
 hsa-miR-580 miRNA Antagomir |
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| MNH03164 | ABM | 2 x 5.0 nmol | EUR 329 |
 hsa-miR-580-3p Primers |
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| MPH03331 | ABM | 150 ul / 10 uM | EUR 121 |
 hsa-miR-580-5p Primers |
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| MPH03332 | ABM | 150 ul / 10 uM | EUR 121 |
 Antibody) PYK2 (Phospho-Tyr579/580) Antibody |
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| 13230-100ul | SAB | 100ul | EUR 252 |
PYK2 (Phospho-Tyr579/580) Antibody |
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| 13230-50ul | SAB | 50ul | EUR 187 |
 Antibody) SHP-2 (Ab-580) Antibody |
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| 21320-100ul | SAB | 100ul | EUR 252 |
SHP-2 (Ab-580) Antibody |
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| 21320-50ul | SAB | 50ul | EUR 187 |
 Anhydrosafflor yellow B |
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| TBW01543 | ChemNorm | 5mg | Ask for price |
 Safflor Yellow A |
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| TBZ2652 | ChemNorm | unit | Ask for price |
 Yellow Fluorescent Protein |
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| 4998-100 | Biovision | EUR 392 | |
Yellow Fluorescent Protein |
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| 4998-1000 | Biovision | EUR 2513 | |
Yellow Fluorescent Protein |
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| 4998-5000 | Biovision | EUR 6846 | |
 lucifer yellow cadaverine |
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| 80018 | Biotium | 25MG | EUR 149 |
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Description: Minimum order quantity: 1 unit of 25MG |
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 Alizarin yellow GG |
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| AB0011 | Bio Basic | 25g | EUR 58.7 |
 Alizarin yellow R |
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| AB0012 | Bio Basic | 25g | EUR 58.7 |
) Sunset Yellow (BSA) |
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| 20-abx165822 | Abbexa |
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) Sunset Yellow (OVA) |
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| 20-abx165823 | Abbexa |
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 C.I.Vat Yellow 2 |
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| 20-abx181248 | Abbexa |
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 Pigment Yellow 42 |
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| abx185544-100g | Abbexa | 100 g | EUR 356 |
 200UL YELLOW TIPS |
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| T-200-Y | CORNING | 1000/pk | EUR 220 |
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Description: Non Filter Tips; Pipette Tips - Axygen |
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 Naphthol Yellow S |
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| GT6579-100G | Glentham Life Sciences | 100 g | EUR 86 |
Naphthol Yellow S |
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| GT6579-250G | Glentham Life Sciences | 250 g | EUR 150 |
Naphthol Yellow S |
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| GT6579-25G | Glentham Life Sciences | 25 g | EUR 46 |
 Sunset Yellow FCF |
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| GT7438-100G | Glentham Life Sciences | 100 g | EUR 110 |
Sunset Yellow FCF |
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| GT7438-25G | Glentham Life Sciences | 25 g | EUR 58 |
 Basic Yellow 40 |
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| GT8545-25G | Glentham Life Sciences | 25 g | EUR 86 |
 Labeling Tape, Yellow |
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| TP004Y | Bio Basic | 1ROLLS, 1 UNIT | EUR 53.68 |
 0.6ML MICROTUBES. YELLOW |
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| MCT-060-Y | CORNING | 1000/pk | EUR 183 |
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Description: Micro Tubes; Micro Tubes Push Cap- Axygen |
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 1.7ML MICROTUBES. YELLOW |
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| MCT-175-Y | CORNING | 500/pk | EUR 116 |
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Description: Micro Tubes; Micro Tubes Push Cap- Axygen |
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 Hydroxysafflor yellow A |
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| HY-N0567 | MedChemExpress | 10mg | EUR 160 |
Sunset Yellow FCF |
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| HY-D0249 | MedChemExpress | 100mg | EUR 108 |
 Yellow Calibration Particles |
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| YCP-70-5 | Spherotech | 5 mL | EUR 324 |
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Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
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 Alcian Yellow Solution |
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| ANY125 | ScyTek Laboratories | 125 ml | EUR 83 |
Alcian Yellow Solution |
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| ANY3800 | ScyTek Laboratories | 1 Gal. | EUR 454 |
Alcian Yellow Solution |
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| ANY500 | ScyTek Laboratories | 500 ml | EUR 123 |
Alcian Yellow Solution |
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| ANY999 | ScyTek Laboratories | 1000 ml | EUR 178 |
Hydroxysafflor yellow A |
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| N1526-20 | ApexBio | 20 mg | EUR 282 |
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Description: Extracted from Carthamus tinctorius L;Store the product in sealed,cool and dry condition |
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 Blocking Peptide) Phospho-PYK2 (Tyr579/580) Blocking Peptide |
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| AF7383-BP | Affbiotech | 1mg | EUR 195 |
 DAX-J2™ Ratio 580/460 |
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| 16310 | AAT Bioquest | 1 mg | EUR 393 |
 hsa-miR-580-3p miRNA Inhibitor |
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| MIH03165 | ABM | 2 x 5.0 nmol | EUR 176 |
 hsa-miR-580-5p miRNA Inhibitor |
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| MIH03166 | ABM | 2 x 5.0 nmol | EUR 176 |
 hsa-miR-580-3p miRNA Antagomir |
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| MNH03165 | ABM | 2 x 5.0 nmol | EUR 329 |
 hsa-miR-580-5p miRNA Antagomir |
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| MNH03166 | ABM | 2 x 5.0 nmol | EUR 329 |
 MemBriteâ„¢ Fix 568/580, Trial Size |
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| 30095-T | Biotium | 1KIT | EUR 222 |
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Description: Minimum order quantity: 1 unit of 1KIT |
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 Antibody) Zinc Finger Protein 580 (ZNF580) Antibody |
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| abx030431-400ul | Abbexa | 400 ul | EUR 523 |
Zinc Finger Protein 580 (ZNF580) Antibody |
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| abx030431-80l | Abbexa | 80 µl | EUR 286 |
 Conjugated Antibody) PYK2 (Phospho-Tyr579/580) Conjugated Antibody |
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| C13230 | SAB | 100ul | EUR 397 |
 Recombinant human Zinc finger protein 580 |
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| P2142 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human Zinc finger protein 580 |
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 Long trebler phosphoramidite |
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| A8151-250 | ApexBio | 250 mg | EUR 340 |
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Description: Long trebler phosphoramidite is a branching reagent for oligonucleotide synthesis allowing to synthesize branched DNA structures using standard DNA synthesizer. |
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 Hydroxy safflor Yellow A |
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| TB0782-1000 | ChemNorm | 20mg | EUR 207 |
 Antibody) Sunset Yellow (SY) Antibody |
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| 20-abx100868 | Abbexa |
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 Yellow Fever NS1 Antibody |
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| abx024098-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024122-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024123-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024124-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024125-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024126-1mg | Abbexa | 1 mg | EUR 773 |
Yellow Fever NS1 Antibody |
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| abx024127-1mg | Abbexa | 1 mg | EUR 773 |
 200UL YELLOW TIPS, RACKED |
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| T-200-Y-R | CORNING | 960/pk | EUR 125 |
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Description: Non Filter Tips; Pipette Tips - Axygen |
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 Fluorescent Light Yellow Particles |
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| FP-15045-2 | Spherotech | 2 mL | EUR 283 |
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Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
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) Martius Yellow (C.I. 10315) |
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| GL3107-100G | Glentham Life Sciences | 100 g | EUR 198 |
Martius Yellow (C.I. 10315) |
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| GL3107-25G | Glentham Life Sciences | 25 g | EUR 90 |
) Metanil Yellow (C.I. 13065) |
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| GT1665-100G | Glentham Life Sciences | 100 g | EUR 70 |
Metanil Yellow (C.I. 13065) |
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| GT1665-250G | Glentham Life Sciences | 250 g | EUR 110 |
Metanil Yellow (C.I. 13065) |
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| GT1665-50G | Glentham Life Sciences | 50 g | EUR 54 |
) Alcian Yellow (C.I. 12840) |
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| GT4246-1G | Glentham Life Sciences | 1 g | EUR 134 |
) Dimethyl Yellow (C.I. 11020) |
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| GT5992-100G | Glentham Life Sciences | 100 g | EUR 90 |
Dimethyl Yellow (C.I. 11020) |
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| GT5992-25G | Glentham Life Sciences | 25 g | EUR 54 |
Dimethyl Yellow (C.I. 11020) |
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| GT5992-500G | Glentham Life Sciences | 500 g | EUR 190 |
) Quinoline Yellow (C.I. 47000) |
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| GT7040-100G | Glentham Life Sciences | 100 g | EUR 118 |
Quinoline Yellow (C.I. 47000) |
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| GT7040-250G | Glentham Life Sciences | 250 g | EUR 198 |
Quinoline Yellow (C.I. 47000) |
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| GT7040-25G | Glentham Life Sciences | 25 g | EUR 62 |
) Nitrazine Yellow (C.I. 14890) |
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| GT9637-25G | Glentham Life Sciences | 25 g | EUR 213 |
Nitrazine Yellow (C.I. 14890) |
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| GT9637-5G | Glentham Life Sciences | 5 g | EUR 78 |
 YELLOW Lysis Kit 50 |
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| YELLOWE1 | Next Advance | 50pack | EUR 175 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. |
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 YELLOW Lysis Kit 250 |
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| YELLOWE5 | Next Advance | 250pack | EUR 548 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. |
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 200UL YELLOW REFERENCE TIPS |
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| TR-222-Y | CORNING | 1000/pk | EUR 213 |
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Description: Non Filter Tips; Pipette Tips - Axygen |
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 80-Well Rack, Yellow |
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| R567-Y | Bio Basic | 1 UNIT | EUR 52.51 |
) Metanil Yellow (Aqueous Solution) |
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| MYQ500 | ScyTek Laboratories | 500 ml | EUR 98 |
Metanil Yellow (Aqueous Solution) |
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| MYQ999 | ScyTek Laboratories | 1000 ml | EUR 127 |
 Naphthol Yellow S Solution |
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| NYS125 | ScyTek Laboratories | 125 ml | EUR 101 |
Naphthol Yellow S Solution |
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| NYS500 | ScyTek Laboratories | 500 ml | EUR 170 |
Naphthol Yellow S Solution |
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| NYS999 | ScyTek Laboratories | 1000 ml | EUR 242 |
, Colorimetric) CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| CBA-135 | Cell Biolabs | 96 assays | EUR 821 |
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Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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The effectiveness of the new-generation nets has been confirmed in some research, however their particular impact on mosquitoes carrying detoxing enzymes and people carrying each detoxing enzymes and the knock-down resistance gene in Benin is just not well-known. Thus, the target of this research is to judge the efficacy of LLINs handled with PBO on multi-resistant Anopheles gambiae s.l.